Margaret Scull
Margaret Scull
Biography
I received my bachelor’s degree in biology from Duke University and my Ph.D. in microbiology and immunology from the University of North Carolina at Chapel Hill. After completing post-doctoral research at the Rockefeller University under Dr. Charles Rice, I joined the faculty at the University of Maryland, College Park as an assistant professor in 2016.
Graduate Program Affiliations
- Biological Sciences (BISI): Molecular and Cell Biology (MOCB)
Research Interests
My lab at UMD works at the interface of virology and cell biology. Specifically, our work focuses on virus-host interactions in the airway epithelium – the primary target for infection by influenza virus and other clinically relevant respiratory viruses. My lab uses a variety of tools, including microscopy, deep sequencing technology, viral genetics, and in vitro primary cell model systems to understand mechanisms of host restriction and innate defense against viral infection.
Education & Positions
- B.S., Duke University, 2001
- Ph.D., The University of North Carolina, Chapel Hill, 2009
- Postdoctoral research, The Rockefeller University, 2010-2016
All Publications
Latest Papers
IMPAIRED NEURAMINIDASE AND POLYMERASE ACTIVITIES CORRESPOND WITH LIMITED AEROSOL INFECTIVITY OF B3.13 AND D1.1 H5N1 LINEAGES IN HUMAN RESPIRATORY CULTURES
Author(s): L. Claire Gay, Dikshya Regmi, Flavio Cargnin Faccin, et. al
UMD Author(s): Margaret Scull
RIG-Ing the system to balance immune activation and inflammatory tissue damage in the airways
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Cell Systems
Author(s): Alec P. Pankow, Margaret A. Scull, Brad R. Rosenberg
UMD Author(s): Margaret Scull
Methods for Discerning the Impact of Mucus on Host Defenses Against Viral Infection
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Current Protocols
Author(s): Maria Corkran, Allison Boboltz, Gregg A. Duncan, et. al
UMD Author(s): Margaret Scull, Gregg Duncan
Human Stimulator of Interferon Genes Promotes Rhinovirus C Replication in Mouse Cells In Vitro and In Vivo
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Viruses
Author(s): Monty E. Goldstein, Maxinne A. Ignacio, Jeffrey M. Loube, et. al
UMD Author(s): Margaret Scull
MUC5B mobilizes and MUC5AC spatially aligns mucociliary transport on human airway epithelium
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Science advances
Author(s): Daniel Song, Ethan Iverson, Logan Kaler, et. al
UMD Author(s): Margaret Scull
Membrane-Tethered Mucin 1 Is Stimulated by Interferon and Virus Infection in Multiple Cell Types and Inhibits Influenza A Virus Infection in Human Airway Epithelium
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mBio
Author(s): Ethan Iverson, Kira Griswold, Daniel Song, et. al
UMD Author(s): Margaret Scull
Rhinovirus C replication is associated with the endoplasmic reticulum and triggers cytopathic effects in an in vitro model of human airway epithelium
Author(s): Talita B. Gagliardi, Monty E. Goldstein, Daniel Song, et. al
UMD Author(s): Margaret Scull, Gregg Duncan
Membrane-Tethered Mucin 1 is Stimulated by Interferon in Multiple Cell Types and Antagonizes Influenza A Virus Infection in Human Airway Epithelium
Author(s): Ethan Iverson, Kira Griswold, Daniel Song, et. al
UMD Author(s): Margaret Scull
Leveraging 3D Model Systems to Understand Viral Interactions with the Respiratory Mucosa
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Viruses
Author(s): Ethan Iverson, Logan Kaler, Eva L. Agostino, et. al
UMD Author(s): Margaret Scull
miRNA independent hepacivirus variants suggest a strong evolutionary pressure to maintain miR-122 dependence
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PLoS pathogens
Author(s): Yu, Y., Scheel, T.K.H., Luna, J.M., et. al
UMD Author(s): Margaret Scull




