William Jeffery
William Jeffery
Affiliate Professor of Cell Biology and Molecular Genetics
Teaching
- Developmental Biology
- Developmental Genetics
Graduate Program Affiliations
- Biological Sciences (BISI): Behavior, Ecology, Evolution, and Systematics (BEES)
- Biological Sciences (BISI): Molecular and Cell Biology (MOCB)
Research Interests
I am interested in the evolution of development. Several different animals are used in my research. The teleost Astyanax mexicanus is a single species with eyed surface dwelling and blind cave dwelling forms. I want to understand the developmental and evolutionary mechanisms responsible for phenotypic changes in Astyanax cavefish. I am also interested in the ancestry of the neural crest and regeneration in chordates. For this research I use sea squirts (ascidians), especially Ciona intestinalis, which has a completely sequenced genome.
Awards
- Fellow, AAAS
- Fellow, Linnean Society
- Honorary Member, Saint Petersburg (Russia) Society of Naturalists
- 2010, Karst Waters Institute Research Award
- 2012 Alexander Kowalevsky Medal
- 2018, National Speleological Society Science Award
- 2021, CMNS Board of Visitors Distinguished Faculty Award
Education
- Ph.D., Biology, University of Iowa, 1971. Evolution of developmental mechanisms in chordates.
All Publications
Latest Papers
Convergent evolution of albinism in cave animals is driven by shared mechanisms and adaptive advantages
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Communications Biology
Author(s): Helena Bilandžija, Kenneth J. Renner, Helena Ćetković, et. al
UMD Author(s): William Jeffery
Environmental hypoxia controls the evolution of cavefish heart asymmetry
Author(s): Mandy Ng, Helena Bilandzija, William R. Jeffery
UMD Author(s): William Jeffery
REGENERACIJA PRI PLAŠČARJU CIONA
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Pomurska obzorja
Author(s): Špela Gorički, William Jeffery
UMD Author(s): William Jeffery
A common mechanism and multiple advantages of pigment loss underlie the convergent evolution of albinism in cave animals
Author(s): Helena Bilandžija, Kenneth J. Renner, Helena Ćetković, et. al
UMD Author(s): William Jeffery
Hypoxia-Sonic Hedgehog Axis as a Driver of Primitive Hematopoiesis Development and Evolution in Cavefish
Author(s): Corine M. van der Weele, Katrina C. Hospes, Katherine E. Rowe, et. al
UMD Author(s): William Jeffery
Natural reversal of cavefish heart asymmetry is controlled by Sonic Hedgehog effects on the left-right organizer
Author(s): Mandy Ng, Li Ma, Janet Shi, et. al
UMD Author(s): William Jeffery
Differentially expressed chaperone genes reveal a stress response required for unidirectional regeneration in the basal chordate Ciona
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BMC biology
Author(s): William R. Jeffery, Bo Li, Mandy Ng, et. al
UMD Author(s): William Jeffery
Apoptosis is a generator of Wnt-dependent regeneration and homeostatic cell renewal in the ascidian Ciona
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Biology open
Author(s): William R. Jeffery, Špela Gorički
UMD Author(s): William Jeffery
Apoptosis is a generator of Wnt-dependent regeneration and homeostatic cell renewal in the ascidianCiona
Author(s): William R. Jeffery, Spela Goricki
UMD Author(s): William Jeffery
Astyanax surface and cave fish morphs
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EvoDevo
UMD Author(s): William Jeffery


