Yanxin Liu
Yanxin Liu
Education
- Ph. D. in Physics, University of Illinois at Urbana-Champaign, 2013
- M. S. in Physics, Florida International University, 2007
- B. S. in Applied Physics, Xi’an Jiaotong University, 2004
Professional Experience
- Assistant Professor, Department of Chemistry and Biochemistry and Institute for Bioscience and Biotechnology Research, University of Maryland, College Park (2022/1-present)
- Postdoctoral Fellow & Associate Specialist, Department of Biochemistry and Biophysics, University of California, San Francisco (2014/08-2021/12)
- Postdoctoral Research Associate, Beckman Institute and Department of Physics, University of Illinois at Urbana-Champaign (2013/07-2014/07)
Graduate Program Affiliations
- Biological Sciences (BISI): Computational Biology, Bioinformatics, and Genomics (CBBG)
- Biological Sciences (BISI): Molecular and Cell Biology (MOCB)
- Chemistry & Biochemistry
Research Interests
- Cryo-electron microscopy and large-scale molecular dynamics simulation
- Chaperone mediated protein folding and maturation
- Protein translocations into membrane-bound organelles
- Cellular stress response
Major Recognitions and Honors
- UCSF-CCSF Inclusive Mentoring Fellow, University of California, San Francisco & City College of San Francisco, 2021
- Independent Postdoctoral Research Award, UCSF Program for Breakthrough Biomedical Research (PBBR), 2019-2020
- American Heart Association Postdoctoral Fellowship, American Heart Association, 2018-2020
- Helen Hay Whitney Postdoctoral Fellowship, Howard Hughes Medical Institute and Helen Hay Whitney Foundation, 2015-2018
- Outstanding Reviewer, Computers in Biology and Medicine, Elsevier, 2015
- Chemical Computing Group Excellence Award, American Chemical Society, 2013
- Student Research Achievement Award, Biophysical Society 56th Annual Meeting, 2012
Research in Dr. Yanxin Liu’s lab focuses on the molecular and structural understanding of protein complexes that are related to human diseases. We employ an integrative approach that combines biophysics, biochemistry, structural biology, and computational modeling. In particular, we are specialized in emerging technologies of high-resolution single-particle cryo-electron microscopy, cryo-electron tomography, and large-scale atomistic molecular dynamics simulation. The current research areas include:
- Chaperone assisted protein folding.
- Protein translocations into membrane-bound organelles.
- Cellular stress response.
BISI Concentration Areas
Computational Biology, Bioinformatics, and GenomicsMolecular and Cellular Biology
Latest Papers
Transgene-free genome editing in citrus and poplar meristem tissues via biolistic ribonucleoprotein delivery of CRISPR-Cas9
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Plant Cell Reports
Author(s): Dhiôvanna Corrêia Rocha, Miracle Osazee Omoregbee, Weifeng Luo, et. al
UMD Author(s): Yanxin Liu
Magnetodynamics of short nanoparticle chains
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Scientific Reports
Author(s): Thinh Q. Bui, Samuel D. Oberdick, Frank M. Abel, et. al
UMD Author(s): Yanxin Liu
Kinetic investigation of calcium-induced Sorcin aggregation by stopped-flow light scattering
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Biochemical Journal
Author(s): Qiushi Ye, Kathleen Joyce Carillo, Nicolas Delaeter, et. al
UMD Author(s): Yanxin Liu
Recombinant Expression and Purification of the Cyanobacterial Chaperone HtpG from Synechococcus elongatus PCC 7942
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Methods and Protocols
Author(s): Liqun Jiang, Ibrahim D. Boyenle, Nicolas Delaeter, et. al
UMD Author(s): Yanxin Liu
Cryo-EM structures of HCV E2 glycoprotein bound to neutralizing and non-neutralizing antibodies determined using bivalent Fabs as fiducial markers
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Communications Biology
Author(s): Salman Shahid, Sharanbasappa S. Karade, S. Saif Hasan, et. al
UMD Author(s): Yanxin Liu
The Lassa Virus Stable Signal Peptide Undergoes a Conformational Change to Aid Viral Fusion
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Chemistry – A European Journal
Author(s): Shane D. Collins, Liqun Jiang, Yanxin Liu, et. al
UMD Author(s): Yanxin Liu
Solution NMR backbone resonance assignment of the full-length resistance-related calcium-binding protein Sorcin
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Biomolecular NMR Assignments
Author(s): Kathleen Joyce Carillo, Yanan He, Qiushi Ye, et. al
UMD Author(s): Yanxin Liu
In situ cryo-electron tomography reveals the asymmetric architecture of mammalian sperm axonemes.
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Nature structural & molecular biology
Author(s): Chen Z, Greenan GA, Shiozaki M, et. al
UMD Author(s): Yanxin Liu
CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes.
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bioRxiv : the preprint server for biology
Author(s): Gupta M, Azumaya CM, Moritz M, et. al
UMD Author(s): Yanxin Liu