Jeffrey DeStefano

Portrait of Jeffrey DeStefano

Jeffrey DeStefano

Cell Biology & Molecular Genetics Professor
jdestefa@umd.edu 3130 Bioscience Research Bldg.
301 405 5449

Teaching

  • General Virology (BSCI437)
  • Graduate Virology (CBMG688K)

Graduate Program Affiliations


Research Interests

HIV and poliovirus replication and recombination


Education

  • Ph.D., University of Connecticut, 1990

All Publications

Pubmed logo


BISI Concentration Areas

Molecular and Cellular Biology

Latest Papers

A novel aptamer-based dNTP assay reveals that intact HIV virions are highly stable and do not contain enough dNTPs to support DNA synthesis

| Journal of Virology
Author(s): Urja Biswas, Cynthia Bernal, Ruofan Wang, et. al
UMD Author(s): Jeffrey DeStefano, Urja Biswas


Inhibition of SARS-CoV-2 infection in human airway epithelium with a xeno-nucleic acid aptamer

| Respiratory Research
Author(s): Niayesh Razi, Weizhong Li, Maxinne A. Ignacio, et. al
UMD Author(s): Jeffrey DeStefano


Cryo-EM structure of the HIV-1 Pol polyprotein provides insights into virion maturation

| Science advances
Author(s): Jerry Joe E. K. Harrison, Dario Oliveira Passos, Jessica F. Bruhn, et. al
UMD Author(s): Jeffrey DeStefano


Selection of Primer–Template Sequences That Bind with Enhanced Affinity to Vaccinia Virus E9 DNA Polymerase

| Viruses
Author(s): Jeffrey J. DeStefano, Frédéric Iseni, Nicolas Tarbouriech
UMD Author(s): Jeffrey DeStefano


Selection of Primer–Template Sequences That Bind with Enhanced Affinity to Vaccinia Virus E9 DNA Polymerase

| Viruses
Author(s): Jeffrey J. DeStefano, Frédéric Iseni, Nicolas Tarbouriech
UMD Author(s): Jeffrey DeStefano


Structural basis of HIV inhibition by L-nucleosides: Opportunities for drug development and repurposing

| Drug Discovery Today
Author(s): Ruiz, F.X., Hoang, A., Dilmore, C.R., et. al
UMD Author(s): Jeffrey DeStefano


Improving aptamer performance with nucleic acid mimics: de novo and post-SELEX approaches

| Trends in Biotechnology
Author(s): Oliveira, R., Pinho, E., Sousa, A.L., et. al
UMD Author(s): Jeffrey DeStefano


Selection of Primer-Template Sequences That Bind with Enhanced Affinity to Vaccinia Virus E9 DNA Polymerase

| Viruses
Author(s): Destefano, J.J., Iseni, F., Tarbouriech, N.
UMD Author(s): Jeffrey DeStefano


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